The Gale Encyclopedia of Diets: A Guide to Health and Nutrition
Macrovascular disease, or , is the cause of more than half of all mortality in developed countries and the leading cause of death in the United States. It is a progressive disease of the large- and medium-sized . The name is derived from the Greek meaning "gruel" or "paste" and meaning "hardening." Thus, atherosclerosis is the hardening of the arteries due to the accumulation of this paste (commonly called plaque).